Sergio Uribe

1) focus the clinical question;
2) locate literature using bibliographic databases;
3) use original journal articles;
4) use systematic reviews with confidence;
5) use text-books with caution;
6) read the preappraised literature;
7) abandon advertisements;
8) throw away the throwaways;
9) teach yourself critical appraisal;
10) be wary of overinterpretation of substitute end points;
11) teach yourself basic clinical statistics;
12) engage in effective browsing;
13) store useful articles;
14) invest in informatics; and
15) implement evidence-based practice guidelines.

Fuente: Cook DJ, Meade MO, Fink MP. How to keep up with the critical care literature and avoid being buried alive. Crit Care Med. 1996 Oct;24(10):1757-68.

• elección de la revista a publicar, basado en el área de interés de la revista y en sus potenciales lectores,

• envío del manuscrito,

• revisión general del editor, quien verifica si el manuscrito está dentro del área de interés de la revista y cumple con los requisitos mínimos (problema nuevo, interesante y resultados aparentemente válidos). En caso negativo, el manuscrito se rechaza, y en caso afirmativo, se envía a revisores

• revisión por pares revisores, como su nombre lo indica, revisan el articulo y emiten un juicio crítico. Este juicio puede rechazar el artículo para su publicación, aceptarlo con correcciones mayores, las que deben ser realizadas por los autores (salvo muy específicas, contadas y excepcionales circunstancias), aceptación con correcciones menores o, en muy raras ocasiones, aceptar tal cual. En caso que los revisores requieran cambios, pueden haber usualmente entre dos y cinco revisiones adicionales, dependiendo de la claridad de cambios requeridos por los revisores. Luego de esto, una vez aceptado el artículo por el editor, hay una o dos pruebas de imprenta y luego el artículo está listo para su publicación

Saludos desde Chile, les solicito respetuosamente si me pudiese informar del estado de proceso editorial del artículo que enviamos en diciembre del 2001 y aprobado para publicación en mayo 2012 en vuestra revista. Desde ya agradezco su atención.

Por favor envie el título del artículo.

Atentamente Dr. Sergio Uribe, me apena mucho informarle que tuvimos la pérdida de muchos archivos de la revista, entre los que se encontraba su artículo, ahora estamos en proceso de automatización por el Open Journal Systems, por lo que le pido por favor que coloque la última versión en la plataforma on line de la revista , esta es la dirección: http://www.revestomatologia.sld.cu/index.php/est
Se registra y como autor coloca el artículo según los 5 pasos indicados. Es un deseo de la editorial de ciencias médicas la automatización de todas las revista y nosotros estamos en ese proceso. Muy agradecida por su amable cooperación, rogándole sepa disculparnos, un afectuoso saludo,

Deseamos un FELIZ 2013, lleno de éxitos personales y profesionales.
Comité Editorial, Revista Cubana de Estomatología

Por favor deben subir de nuevo el artículo en word, en el formato que está no abre

...como recordará le expliqué que tuvimos problemas con la información guardada en una computadora que se dañó. Ahora solo tenemos lo que hay en la plataforma que lo conserva todo.

sudo apt-get update && sudo apt-get upgrade

sudo add-apt-repository ppa:tualatrix/ppa 
sudo apt-get update && sudo apt-get install ubuntu-tweak

sudo add-apt-repository ppa:bikooo/glippy
sudo apt-get update && sudo apt-get install glippy

sudo apt-get install nautilus-open-terminal

sudo apt-add-repository ppa:diesch/testing
sudo apt-get update && sudo apt-get install classicmenu-indicator

sudo apt-get install lo-menubar

sudo apt-get install cups-pdf

sudo add-apt-repository ppa:markjtully/ppa 
sudo apt-get update && sudo apt-get install unity-lens-academic unity-scope-zotero - 

gksudo gedit

#!/usr/bin/env xdg-open
[Desktop Entry]
Type=Application
Name=Zotero
GenericName=Bibliography Manager
Icon=/opt/Zotero_linux-x86_64/chrome/icons/default/default48.png
Exec= /opt/Zotero_linux-x86_64/zotero %f
Categories=Office
Terminal=false

ln -s /home/sergio/zotero_files /zotero-dropbox

sudo add-apt-repository ppa:webupd8team/java 
sudo apt-get update && sudo apt-get install oracle-java7-installer

Install R

deb http://<my.favorite.cran.mirror>/bin/linux/ubuntu precise/
$ sudo apt-get update
$ sudo apt-get install r-base

sudo apt-key adv --keyserver keyserver.ubuntu.com --recv-keys E084DAB9

$ sudo apt-get install wajig
$ wajig install libgtk2.0-dev libxml2-dev

 > install.packages("rattle")
 > library("rattle")
 > rattle()

Hace tiempo escribí acerca del escándalo que es ver como los aranceles que pagan los estudiantes de las Ues privadas terminan pagando publicidad para atraer más postulantes en vez de pagando profesores, bibliotecas o investigación..

Ahora hay unos datos que permiten hacer una estimación más precisa de los "gastos" o "inversión" (como quiera que lo llamen) en publicidad de las universidades.

El año 2008 se gastaron $ 57.259.700.000, unos U$ 119.308.440 (fuente). De estos, cerca del 83% de ese gasto correspondió a universidades privadas (fuente), o sea, las ues privadas gastaron cerca de $ 47.525.551.000 mientras que las del CRUCh cerca de $ 9.734.149.000. Considerando que la matrícula de las ues el 20085 fue de 504.000 estudiantes, distribuidos en 257.000 de CRUCh y 246.000 de ues privadas (fuente), en promedio, cada estudiante de universidad tradicional pagó $ 13.742 anuales en publicidad de su universidad, mientras que un estudiante de universidad privada pagó $ 193.079 por el mismo concepto. Por supuesto, esto es un promedio, ya que la diferencia entre el gasto en publicidad de una u privada puede ser hasta 10 veces (fuente). Sin embargo, lo que está claro que existe una asociación entre gasto publicitario y calidad, de manera que las ues que gastan más en publicidad tienen peor calidad (fuente). Vale la pena darle un vistazo a los antecedentes recogidos por la Comisión de la Cámara de Diputados aquí


Y que pasa si el "emprendimiento" sale mal? Simple, PIDAMOS QUE EL ESTADO SE HAGA CARGO DEL NEGOCIO!

Peor aun, algunos hablan del "rol social" de las universidades que lucran, arguyendo que permiten que jóvenes que no recibieron una buena educación primaria accedan a la educación superior. Sin embargo, los mismos dueños de las Ues privadas son asimismo dueños de los bancos que ofrecen créditos para estos estudiantes. Esta vía del lucro es COMPLETAMENTE legal, y explica el interés de los "inversionistas" de las ues privadas en capturar la mayor cantidad de postulantes, independiente de si estos tienen o no las capacidades o habilidades que requieren los estudios universitarios. Sin embargo, las ues privadas prefieren gastar en publicidad para captar más "clientes" que en la educación o ayuda a estos estudiantes.

los planteles privados invertían MM$ 22.625 en publicidad, mientras que únicamente MM$ 6.750 en becas. “En el CRUCh, en cambio, las cifras eran MM$ 4.618 y MM$ 17.909. (fuente)

"Professor, your lectures are a disgrace to the university"

Estaba en una fila el otro día y escuche una conversación entre adolescentes:

- y a que u vas a postular?
- a la "U Privada 1", es super buena!
- ah si? que buena, yo a la "U Privada 2", es super buena también

Caries in its simplest expression consists in a chemical dissolution of the calcium salts of the tooth by lactic acid, followed by the decomposition of the organic matrix, or gelatinous body, which, in the dentin, is left after the solution of the calcium salts.
...always begins upon the surface, never in the interior. Decay of the teeth is therefore caused by an agent acting from without the tooth, never from within the tooth. It is something extraneous to the tooth, acting upon the surface in the beginning and penetrating little by little into its substance

The progress of caries is limited, or even stopped, in a number of different ways.

...it becomes the duty of the dentist to prescribe the manner of its use; not only to prescribe the manner of use, but to teach his patients the correct use of the brush.
There are very few persons who need other than the ordinary straight tooth brush. A cheap tooth brush is generally the best tooth brush, because it is small, there are not so many bristles in it, and they will get in between the teeth better. Examinations should be made at intervals to see that regular and correct habits become fixed

It is intrinsically wrong to treat tbe subject of filling teeth simply from the mechanical standpoint; it is wrong in that it tends to produce in the minds of students the idea that filling teeth is a purely mechanical pursuit. This is far from the proper conception of the facts. In filling teeth, the closest use of our knowledge of the pathology of dental caries and of the local conditions of its occurrence, and of its recurrence after fillings have been made, should be put to full use in every case, in order that the greatest benefit may be derived from filling operations

Fillings are not curative in the same sense that vaccination is curative against smallpox — preventive; such remedies remove the tendecy to disease; something of a material nature is introduced into the blood and cellular elements of the whole body that tends to counteract the disease. Nothing of this kind is done in filling teeth. No systemic change is produced as a direct effect. That is to say, fillings do not remove the tendency to caries, and the curative effect of a filling is literally no broader than its outline.

It must be understood that treatment by filling should be supplemented and supported, in all cases of considerable susceptibility to caries of the teeth, by fairly vigorous and healthful chewing of food and by artificial cleaning with the brush in the hands of the patient. For this purpose, careful training of the individuals should be seriously undertaken by the dentist with the same care that he would bestow upon any operation he performs for their relief.

What should be considered a permanent filling? What do we mean by permanent?

...incipient decay of the enamel or the deeioer decays of the proximal surfaces will be stopped, provided the surface is such that it can be kept fairly clean.

You don't have to burn books to destroy a culture. Just get people to stop reading them. ― Ray Bradbury

Minimal intervention dentistry: part 4. Detection and diagnosis of initial caries lesions.

Br Dent J. 2012 Dec;213(11):551-7

Authors: Guerrieri A, Gaucher C, Bonte E, Lasfargues JJ

Abstract
The detection of carious lesions is focused on the identification of early mineral changes to allow the demineralisation process to be managed by non-invasive interventions. The methods recommended for clinical diagnosis of initial carious lesions are discussed and illustrated. These include the early detection of lesions, evaluation of the extent of the lesion and its state of activity and the establishment of appropriate monitoring. The place of modern tools, including those based on fluorescence, is discussed. These can help inform patients. They are also potentially useful in regular control visits to monitor the progression or regression of early lesions. A rigorous and systematic approach to caries diagnosis is essential to establish a care plan for the disease and to identify preventive measures based on more precise diagnosis and to reduce reliance on restorative measures.

PMID: 23222326 [PubMed - indexed for MEDLINE]

Preparing students to practice evidence-based dentistry: a mixed methods conceptual framework for curriculum enhancement.

J Dent Educ. 2012 Dec;76(12):1600-14

Authors: Palcanis KG, Geiger BF, O'Neal MR, Ivankova NV, Evans RR, Kennedy LB, Carera KW

Abstract
This article describes a mixed methods conceptual framework for evidence-based dentistry to enhance the curriculum at the University of Alabama at Birmingham School of Dentistry. A focus of recent curriculum reform has been to prepare students to integrate evidence-based dentistry into clinical practice. The authors developed a framework consisting of four conceptual phases to introduce curriculum innovation: 1) exploration of the phenomenon; 2) development of two new instruments; 3) data collection, analysis, outcomes, and evaluation; and 4) application to curricular reform. Eight sequential procedural steps (literature review; focus group discussions; development of themes; survey design; internal review; data collection, analysis, and evaluation; development of recommendations with external review; and implementation of recommendations for curricular enhancement) guided the curricular enhancement. Faculty members supported the concept of teaching evidence-based dentistry to facilitate major curriculum reform, and course directors incorporated evidence-based teaching to prepare scientist-practitioners who meet dental performance standards. The new curriculum implemented following completion of the study is in its third year. Much of its structure is based on evidence-based teaching methodologies, and approximately one-third of the content consists of small groups researching clinical problems with applied science and discussing the findings. The framework described in this article proved useful to guide revision of predoctoral clinical education at one dental school and may be useful in other settings.

PMID: 23225679 [PubMed - indexed for MEDLINE]

I’m putting this here to get some attention.

There’s a documentary in production, or which was in production, which was a mini series about all things 8-bit consoles and computers. It’s called “8 Bit Generation”. It has trailers up. The trailers are fairly incredible.

These trailers are so nice looking, so well shot, so beautiful and so filled with KILLER interviews, I nearly quit documentary filmmaking when I saw them – someone was doing things a billion times better than I could ever do. I emotionally recovered.

These fellows traveled the world and got all sorts of amazing subjects. Among the ones that blew me away was an actual interview with Jack Tramiel. I’d tried – he’d turned me down. And he’s gone, people. This interview they have is it.

So, in 2011 they put up a trailer, and some of the music they had wasn’t cleared, so they took those down and put up new, cleared trailers. Good enough, although that does mean a lot of articles on them point to the missing Vimeo links. But rest assured, things were looking good. They had a website, you could order stuff, you could see how they were going to have a deluxe version (which I ordered) and a whole bunch of features.

This thing looked AWESOME.

And then, poof.

Here’s the website as it used to look. It’s gone now.

They are missing in action. Totally gone. The domain has a year to expire, but there’s no website for it.

Zoe Blade, who has done a bunch of soundtrack work with me, did the soundtrack work with the documentary as well. She’s gone ahead and put the Soundtrack Album up for sale. Take a listen, it’s fantastic stuff.

Now, I’m a realistic guy. I deal with people working on documentaries for years and there’s ups and downs the whole way. It’s kind of The Deal. One of the facts is everything takes longer than it should – the making, the editing, the packaging, the finishing. It just does.

I keep track of a few dozen projects out there. Some take a long time, some go dormant, some live again. I got it.

But this one… this one was special. Unique interviews with unique people. This was going to be a blockbuster.

Guys? Everything OK? Need help?

UPDATE: Through various channels, I am told that the current situation is one edited episode and some potential financial issues with getting the film done. I continue to offer my support in finishing this film, and wish the producers the best in bringing the project to fruition.

Body mass index and dental caries in children and adolescents: a systematic review of literature published 2004 to 2011.

Syst Rev. 2012 Nov 21;1(1):57

Authors: Hooley M, Skouteris H, Boganin C, Satur J, Kilpatrick N

Abstract
ABSTRACT: The objectiveThe authors undertook an updated systematic review of the relationship between body mass index and dental caries in children and adolescents. METHOD: The authors searched Medline, ISI, Cochrane, Scopus, Global Health and CINAHL databases and conducted lateral searches from reference lists for papers published from 2004 to 2011, inclusive. All empirical papers that tested associations between body mass index and dental caries in child and adolescent populations (aged 0 to 18 years) were included. RESULTS: Dental caries is associated with both high and low body mass index. CONCLUSION: A non-linear association between body mass index and dental caries may account for inconsistent findings in previous research. We recommend future research investigate the nature of the association between body mass index and dental caries in high and low body mass index groups and how factors such as socioeconomic status mediate the association between body mass index and dental caries.

PMID: 23171603 [PubMed - as supplied by publisher]

Most of us would agree that doctors should not treat patients without their consent, except in special cases like emergency care for an unconscious patient.  It’s not enough for doctors to ask “Is it OK with you if I do this?” They should get informed consent from patients who understand the facts, the odds of success, and the risk/benefit ratio of treatments. The ethical principle of autonomy requires that they accept or reject treatment based on a true understanding of their situation and on their personal philosophy. Numerous studies have suggested that patients are giving consent based on misconceptions. There is a failure of communication: doctors are not doing a good job of providing accurate information and/or patients are failing to process that information. I suspect it is a combination of both.

An article in The New England Journal of Medicine reports that while the great majority of patients with advanced lung cancer and colorectal cancer agree to chemotherapy, most of them have unreasonable expectations about its benefits. For some cancers chemotherapy can be curative, but for metastatic lung or colorectal cancer it can’t. For these patients, chemotherapy is only used to prolong life by a modest amount or to provide palliation of symptoms. Patients were asked questions like “After talking with your doctors about chemotherapy, how likely did you think it was that chemotherapy would… help you live longer, cure your cancer, or help you with problems you were having because of your cancer?” A whopping 69% of lung cancer patients and 81% of colorectal cancer patients believed it was likely to cure their cancer, and most of these thought it was very likely.

False beliefs were:

• More common in colorectal cancer than in lung cancer
• Three times as high for non-white and Hispanic patients
• Twice as high for patients who rated their communication with their physician very favorably.

There was no correlation between inaccurate beliefs and educational level, income, functional status, or the patient’s role in decision-making.

It’s ironic in a way. These patients thought chemotherapy was better than it really is, but generally chemotherapy has had a very bad press. It has been so demonized that some patients reject it out of hand, and those who accept it often find it nowhere near as bad as they had been led to believe. An e-mail correspondent wanted to label chemotherapy “quackery” because he said it only offered a 2-5% benefit for cancer survival. I had to explain to him that “quackery” refers to treatments with zero benefit, that it is meaningless to speak of cancer as a single entity, that the benefits of chemotherapy depend on the type and stage of cancer, that chemotherapy is curative for some types of cancer, and that it is also used for its adjuvant and palliative effects.

He also asked, “Surgery for cancer has a much greater success rate than 2-5% right?” I explained that it is meaningless to talk about the success rate of “surgery for cancer.” You have to look at specific types and stages of cancer. The success rate for breast cancer surgery in ductal carcinoma in situ stage 0 is 98% for 10-year survival. For pancreatic cancer, virtually all patients are dead within 7 years of surgery. It makes a huge difference whether metastasis has already occurred at the time of surgery. And some cancers, like blood cancers (leukemia, etc.), are not treatable with surgery.

I don’t think oncologists are deliberately lying to patients about chemotherapy. But I suspect they may be carefully choosing their words to put it in a more favorable light, since they naturally want to do something and to offer the patient hope. This may not be operating on a conscious level. And the very fact that they are offering chemotherapy to a patient gives it credibility, no matter what they say.

Whether or not the oncologist offers subtly biased information, the patients’ own biases contribute to poor communication. They want to survive. They want to have hope. It is only natural for them to put a positive slant on what they are told; they may not try to understand the negatives or they may minimize their importance. In some cases, they simply refuse to hear the facts and continue to believe what they want to believe.  This study suggests that patients perceive physicians as better communicators when they convey a more optimistic view of chemotherapy.

Should we accept these misunderstandings because they give patients hope? Should we be concerned that they have not met the standard for giving informed consent for their treatment? Other studies have shown that patients with advanced cancer would accept toxic treatment for even a 1% chance of cure but would be unwilling to accept the same treatment for a substantial increase in life expectancy without cure. So if they are accepting chemotherapy on the basis of these misunderstandings, they are not doing what they say they want to do. The misunderstandings might even interfere with end-of-life planning and care.  Previous studies have shown substantial discrepancies between patients’ and doctors’ estimates of their life expectancy.

Another recent study published in the Annals of Family Medicine showed patients have similar misunderstandings about the value of screening tests and preventive treatments.

• 90% overestimated the effect of breast cancer screening
• 94% overestimated the effect of bowel cancer screening
• 82% overestimated the effect of hip fracture preventive medication
• 69% overestimated the effect of preventive medication for cardiovascular disease.

Doctors also have some serious misunderstandings in these areas. Ina study by Gigerenzer et al. researchers did a survey of 160 gynecologists attending a continuing education session in 2007. They described a patient who has a positive mammogram and who asks her gynecologist whether that means she has cancer for sure, or what the chances are. What would they tell her? They were given the pertinent information (1% prevalence in that population, 90% of women with cancer test positive, 9% of women without cancer test positive). They were given a multiple-choice question with 4 answers: 81%, 90%, 10%, and 1%. The correct answer, which could be easily calculated from the statistics provided, was 9%. The other answers were wrong by an order of magnitude. They could derive the answer from the statistics or they could simply recall what they should have known anyhow. The gynecologists gave answers ranging from 1% to 90%; the majority of them grossly overestimated the probability of cancer as 90% or 81%, and only 21% answered correctly (not even as good as chance). I don’t know about you, but I find that positively frightening.

Conclusion

Doctors and patients have misconceptions about the value of chemotherapy, screening tests, and preventive measures. And probably a lot of other things! If patients are to give truly informed consent, doctors must have accurate science-based information and must find ways of effectively communicating their knowledge to patients without losing their patients’ trust and regard and without destroying hope.

Looking for a visually slick way to browse your music collection in Rhythmbox? The following CoverArt Browser plugin might be just what you’re after… 

As the plugin name implies, CoverArt Browser lets you browse your music collection using cover art rather than the santdard ‘text’ labels that we’re all familiar with.

‘Tiled Wonder’

This plugin has actually been around for some time. Indeed, we first wrote about it back in February 2010. Sadly, development on the plugin stopped around the time of Ubuntu 11.04 meaning that it couldn’t be used with later versions of Ubuntu or Rhythmbox.

Step forward developers ‘fossfreedom‘, and Agustín Carrasco, who have resurrected the tiled-wonder from the ravages of development hell to improve upon it, add new features, and package it up for Ubuntu 12.04 and up.

New Features

The number of features now included in the plugin is extensive.

As well as simply displaying a grid full of album art for browsing, you can

• Drag & Drop cover art on to the browser
• Fetch/search for missing album art
• Display Album & Artist name under the cover
• Double click playing of albums
• Sort covers by album name and artist
• Adjust cover art size
• Multiple user-configurable options to tailor what you see and use.
• Examine and change properties for an album/tracks
• Set ‘CoverArt Browser’ to Rhythmbox’s default view

Features In Use

When the ‘CoverArt’ sidebar item is selected you are presented with a simply grid of album covers.

The CoverArt browser has support for searching. Click on the magnifying glass icon in the search bar to choose any areas to search specifically, or stick with the default which searches all fields’.

Using Ctrl+Click you can choose multiple artists or albums at a time, then right click to queue them up in the playlist – another new feature.

Covers too small? You can change their size via the Preferences dialog of the plugin:

Install CoverArt Browser for Rhythmbox in Ubuntu

First things first: download the plugin

Download Coverart Browser for Ubuntu 12.10

Once the plugin has finished downloading open your file browser and navigate to your Downloads folder. Inside here find the ‘rhythmbox-plugin-coverart-browser.deb‘ file and double-click on it to begin installation via the Ubuntu Software Center.

After installing has finished up open Rhythmbox (be sure to fully exit it first if it is already running), then mouse over the Top Panel in Ubuntu to reveal the App Menu.

Go to:

• Edit > Plugins

In the ‘Configure Plugins’ window that opens check the box next to the ‘CoverArt Browser’ entry to enable it.

If you need to access the Preferences for the plugin at any time simply return to this window, select the CoverArt Browser plugin and click the ‘Preferences‘ button towards the bottom of the window.

Related Posts

• Rhythmbox Cover Art Browser
• ‘WebMenu’ Adds Handy Web Links to Rhythmbox
• Handy Plugin to Sync Last.FM Playcount With Rhythmbox

A recent report from the Joan Ganz Cooney Center has identified that we don't actually know enough about how pre-teens use online social networking. The researchers have done a good job in helping us recognize that younger children are engaged in a range of different ways with online social networks, but that our knowledge and understanding of what that means and how it impacts their lives is pretty much underdone.

Boris SV posted a photo:

...:)

I’m going to let you in on a well-kept secret.

There’s nothing new about “social media.”

Further, most online social sharing still happens outside of social networks.

From the very first email sent by researchers in Switzerland in 1971, to modern sites like Google+ and Pinterest, the Internet, and the valuable content it distributes, have always been social.

The very purpose of the Internet (every blog, website and virtual gathering place within it) is to let people connect, communicate, and collaborate.

So the concept behind Facebook, LinkedIn, and other social networking tools isn’t new. These sites just give us new, sexy, and easy-to use ways to do what we’ve always wanted to do online — exchange ideas and information.

The Internet has always been social, and it always will be. Still not convinced?

Here’s a handy timeline that might dispel any further historical myths about the true nature of the Internet, and where we’re all going with it, together …

Click here to view the full-size graphic.

Embed this infographic on your own site

Copy and paste this code into your blog post or web page:

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About the Author: Beth Hayden is a Senior Staff Writer for Copyblogger Media. Get more from Beth on Twitter and Pinterest.

About the Designer: Rafal Tomal is Copyblogger Media's Lead Designer. Get more from Rafal on Twitter.

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Nature 490 343 doi: 10.1038/490343d

Nature 490 342 doi: 10.1038/490342c

New collaboration patterns are changing the global balance of science. Established superpowers need to keep up or be left behind, says Jonathan Adams.

Nature 490 335 doi: 10.1038/490335a

Nature 490 312 doi: 10.1038/490312c

SandmanLV posted a photo:

Full disclosure could improve health care and restore trust.

Nature 490 322 doi: 10.1038/490322a